Here are a few things to keep in mind when injecting Aimovig:
- Hygiene & safety are essential. Check that the medication is not damaged or expired, wash your hands, and clean the injection site with an alcohol wipe before injecting.
- You might experience side effects. Injection site reactions like pain, redness and itching are quite common and not a cause for concern. Keep a cold compress or ice pack at hand in case you experience these symptoms.
- Dispose of sharps safely. Unlike regular syringes, autoinjector pens don’t have an exposed needle – but they still need to be put in a sharps disposal container.
How effective is Aimovig?
Just like other migraine preventives, the efficacy of Aimovig can vary from person to person. Some might find it very effective, while others might find it doesn’t help much at all.
Two clinical trials were conducted to measure the safety and efficacy of Aimovig in episodic and chronic migraine. Both studies found that Aimovig caused a clinically significant reduction in migraine days. You can see some of the study results in the tables below.
Episodic migraine (4)
| ||Placebo (n = 316)||70mg dose (n = 312)||140mg dose (n = 318)
|Average migraine days per month at baseline||8.23||8.29||8.34
|Average migraine days per month during treatment||6.4||5.06||4.67
|Average reduction in migraine days||‒1.83||‒3.23||‒3.67
|Percentage of patients with 50% or more reduction in monthly headache days||26.2%||43.3%||50.0%
Source: Clinical Trial Identifier NCT02456740 (3)
Chronic migraine (5)
| ||Placebo (n = 267)||70mg dose (n = 178)||140mg dose (n = 182)
|Average migraine days per month at baseline||18.22||17.85||17.78
|Average migraine days per month during treatment||14.04||11.21||11.15
|Average reduction in migraine days||‒4.18||‒6.64||‒6.63
|Percentage of patients with 50% or more reduction in monthly headache days||23.5%||39.9%||41.2%
Source: Clinical Trial Identifier NCT02066415 (4)
If you try Aimovig (or any other CGRP monoclonal antibodies) and you don’t find it effective, don’t be discouraged. Some people will not respond to one CGRP monoclonal antibodies but find another very helpful. You can discuss your options with your doctor.